Eye discomfort
Conditions
Interventions
A commercially available 222 nm Far-UVC disinfection lamp (Care222) or a dummy irradiation device (incorporating an optical LED in place of the 222 nm Far-UVC lamp) is irradiated to the eyes of the st
22 mJ/cm2. The irradiation duration was 3 hours, of which 2 hours were irradiated by the 222 nm Far-UVC disinfection lamp and 1 hour by the dummy irradiation device.
A commercially available 222 nm Fa
11 mJ/cm2. The irradiation duration was 3 hours, of which 1 hours were irradiated by the 222 nm Far-UVC disinfection lamp and 2 hours by the dummy irradiation device.
A commercially available 222 nm F
11 mJ/cm2. The irradiation duration was 3 hours, all with 222 nm Far-UVC disinfection lamps.
A commercially available 222 nm Far-UVC disinfection lamp (Care222) or a dummy irradiation device (incorpor
5.5 mJ/cm2. The irradiation duration was 3 hours, of which 1.5 hours were irradiated by the 222 nm Far-UVC disinfection lamp and 1.5 hours by the dummy irradiation device.
A commercially available 222
Sponsors
Shimane Univesity
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patient must be able to give his/her free and written consent to participate in the study. Must be able to avoid excessive exposure to ultraviolet light (e.g., outdoor sports, swimming, mountain climbing, etc.) at each observation and within 48 hours prior to the time of exposure to ultraviolet light. Visual acuity before enrollment and within 1 week of the scheduled irradiation must meet all of the following conditions Corrected visual acuity of 0.9 or better in each eye Naked eye visual acuity of 0.3 or better with both eyes open (the patient must be able to view images on a monitor during UVC irradiation). The patient must not be undergoing treatment for ocular diseases that affect visual acuity. No use of eye drops or topical facial skin medications
Exclusion criteria
Exclusion criteria: 1) Daily contact lens wearer 2) Intend to wear contact lenses temporarily (e.g., during sports) within 1 week of irradiation. 3) Engaged in an occupation that exposes them to ultraviolet radiation on a daily basis (e.g., working outdoors, welding, etc.) 4) Have obvious ocular disorders (corneal erosion D score > 2 or conjunctival hyperemia score > 2) observed before enrollment and within 1 week of the scheduled irradiation 5) Has dry eye 6) Comorbid atopic dermatitis 7) Sun sensitivity 8) History or family history of hereditary tumors or melanoma 9) Currently participating in another clinical trial involving an intervention or will participate between the date of enrollment in this study and the end date of observation 10) Other patients deemed ineligible by the investigator of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eye discomfort reported by participants at 1 hour, 2 hours, 3 hours (immediately after the end of irradiation), 6 hours and 24 hours after the beginning of irradiation with 222 nm Far-UVC (answers based on a questionnaire). | — |
Countries
Japan
Contacts
Public ContactSachiko Kaidzu
Shimane University Faculty of Medicine Department of Ophthalmology
Outcome results
None listed