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Establishment of a Multiparameter Flow Cytometry (MFC) Method for Measuring Minimal Residual Disease in Acute Myeloid Leukemia

Establishment of a Multiparameter Flow Cytometry (MFC) Method for Measuring Minimal Residual Disease in Acute Myeloid Leukemia - Establishment of MFC Method for Measuring MRD in AML

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000054913
Enrollment
240
Registered
2024-07-09
Start date
2024-05-23
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myeloid Leukemia

Interventions

None listed

Sponsors

Kyushu University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged 16 and older diagnosed with AML who, as of the date of approval for this study, participated in the 'Kyushu Clinical Sample Network (KCNET)' study and who have also consented to the secondary use of their data.

Exclusion criteria

Exclusion criteria: (1) If the principal investigator, research director, or attending physician determines that enrollment in the study is inappropriate. (2) If the collection of samples is deemed unsafe for the patient or donor. (3) If, for any reason, it is difficult to collect samples. (4) If a lack of research funding makes it difficult to maintain the 'Kyushu Clinical Sample Network (KCNET)' study.

Design outcomes

Primary

MeasureTime frame
Correlation between MRD Trends before, during, and after Treatment and Prognosis in AML

Secondary

MeasureTime frame
Correlation between Existing Methods for MRD Detection (such as the LAIP Method in Flow Cytometry, Chimeric Gene PCR, WT1, etc.) and the Flow Cytometry Method Examined in this Study, and Comparison of the Sensitivity of Each Method

Countries

Japan

Contacts

Public ContactTeppei Sakoda

Kyushu University Hospital Hematology, Oncology, and Cardiovascular Medicine

sakoda.teppei.476@m.kyushu-u.ac.jp092-642-5947

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026