Healthy adults
Conditions
Interventions
Intake of test food for 8 weeks
Intake of placebo for 8 weeks
Sponsors
Kracie, Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Subjects aged 20 to 65 at the time of obtaining consent 2.Subjects who carry Akkermansia 3.Subjects who have not taken any foods for specified health uses, functional foods, dietary supplements, that may affect defecation, or who can maintain the same type and frequency of intake of these products they have been taking up until that point during the study period 4.Subjects receiving a sufficient briefing of the objective and content of the present study, fully understanding and agreeing to voluntarily participate in the study and being able to personally sign a written informed consent
Exclusion criteria
Exclusion criteria: 1.Subjects with serious cardio-vascular, hepatic, renal, respiratory, endocrine or metabolic disorders or having a medical history of these disorders 2.Subjects receiving treatment for a gastrointestinal disease currently or those who have had gastrointestinal surgery 3.Subjects who are suffering from or have a history of a disease that may affect defecation 4.Subjects who take regularly pharmaceuticals or quasi-drugs which having the efficacy for microbiome such as intestinal regulator 5.Subjects who have used antibiotics within the past month 6.Subjects with irregular lifestyles due to night shifts 7.Female subjects who are pregnant or lactating, or intending to become pregnant during the study 8.Subjects who took part in another study within 3 months prior to the start of the present study or who is currently taking part in another study 9. Subjects deemed unsuitable by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relative occupancy of Akkermansia after 4 and 8 week of ingestion | — |
Countries
Japan
Contacts
Public ContactAya Takeda
Cykinso, Inc. Medical & Clinical Division
Outcome results
None listed