Enhancing antidepressant effects of Repetitive transcranial magnetic stimulation by bright light exposure

Enhancing antidepressant effects of Repetitive transcranial magnetic stimulation by bright light exposure - Enhancing antidepressant effects of Repetitive transcranial magnetic stimulation by bright light exposure

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000054895

Enrollment

100

Registered

2024-07-07

Start date

2024-07-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

major depressive disorder

Interventions

Bright light exposure is performed at the same time as the rTMS session. Low-intensity light exposure at the same time as the rTMS session. Bright light exposure for the same length of time before the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inpatients receiving rTMS for more than moderate depression that is not responding to pharmacotherapy

Exclusion criteria

Exclusion criteria: 1) Patients with photodermatosis 2) Patients judged to be inappropriate by the principal investigator

Design outcomes

Primary

Measure	Time frame
Change in depressive symptoms questionnaire scores pre- and post-treatment	—

Secondary

Measure	Time frame
Change in insomnia symptoms and change in time production tasks pre- and post-treatment	—

Countries

Japan

Contacts

Public ContactKentaro Nagao

National Institute of Mental Health, National Center of Neurology and Psychiatry Department of Sleep-Wake Disorders

knagao@ncnp.go.jp042-346-2014

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026