Clarification of Aortogenic Stroke by Non-Obstructive General Angioscopy

Clarification of Aortogenic Stroke by Non-Obstructive General Angioscopy - CRYSTAL Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000054818

Enrollment

300

Registered

2024-07-01

Start date

2022-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral infraction

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: acute ischemic stroke are assessed by neurologists and neurosurgeons using CT and MRI to diagnose strokes caused by large or medium vessel occlusion

Exclusion criteria

Exclusion criteria: atherothrombotic brain infarction, aortic dissection, deteriorating condition, not obtained informed consent

Design outcomes

Primary

Measure	Time frame
In this study, we made definitive diagnoses for thrombectomy cases, excluding those with atherothrombotic brain infarction, through discussions with the brain-heart team (BHT). With the cooperation of intravascular endoscopy and the brain-heart team (BHT), it has become possible to classify cases that were previously diagnosed as embolic strokes of undetermined source (ESUS), particularly those of aortogenic stroke.	—

Measure

Time frame

In this study, we made definitive diagnoses for thrombectomy cases, excluding those with atherothrombotic brain infarction, through discussions with the brain-heart team (BHT). With the cooperation of intravascular endoscopy and the brain-heart team (BHT), it has become possible to classify cases that were previously diagnosed as embolic strokes of undetermined source (ESUS), particularly those of aortogenic stroke.

—

Secondary

Measure	Time frame
Using transesophageal echocardiography (TEE), we aim to further stratify ESUS cases and move closer to a definitive diagnosis.	—

Countries

Japan

Contacts

Public ContactMikio Shiba

Osaka Police Hospital Cardiovascular Division

mikio0629@gmail.com06-6771-6051

Outcome results