pancreatic cancer
Conditions
Interventions
Endoscopic transpapillary biliary drainage using 12-Fr plastic stent.
Sponsors
Sendai City Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: a. Those who have been diagnosed as resectable or borderline resectable pancreatic cancer by blood test, imaging or histology. b. Those who need biliary drainage* before preoperative chemotherapy * Total bilirubin =/> 2.0mg/dL or AST =/> 100U/L. c. Those who are planned to receive preoperative chemotherapy after biliary drainage. d. No history of previous biliary stent placement. e. Obtaining written informed consent
Exclusion criteria
Exclusion criteria: a. No tolerance of endoscopic procedures b. ASA class 4 or more c. Post-gastrectomy reconstruction using methods other than Billroth I d. Not intended to receive preoperative chemotherapy e. History of percutaneous transhepatic biliary drainage or endoscopic ultrasound-guided biliary drainage f. Duodenal stenosis is suspected on specific symptoms or imaging studies g. Age < 18 years h. Already enrolled in this clinical trial i. Allergic for contrast j. Pregnancy k. Difficult to follow up l. Judged to be ineligible by investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recurrent biliary obstruction (RBO) rate in the observation period observation period: from the date of biliary drainage to the earliest date of surgery, the decision not to resect pancreatic cancer, or 1 year after biliary drainage. | — |
Secondary
| Measure | Time frame |
|---|---|
| technical success rate, clinical success rate, rate of adverse events related to endoscopic procedures, time to surgical operation, time to recurrent biliary obstruction (TRBO). | — |
Countries
Japan
Contacts
Public ContactHidehito Sumiya
Sendai City Medical Center Department of Gastroenterology
Outcome results
None listed