Chronic obstructive pulmonary dise
Conditions
Interventions
None listed
Sponsors
Tokyo Metropolitan Ebara Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients who were diagnosed with COPD at EBARA Hospital and who gave their consent to participate in this study. The comparison group consisted of healthy adults registered at the Meguro Silver Human Resource Center whose age and gender matched those of the subject group and whose consent to participate in this study had been obtained.
Exclusion criteria
Exclusion criteria: 1) Patients with acute exacerbation of COPD or significant change in symptoms within the past 2 months 2) Patients whose symptoms or physical condition changed drastically in approximately 4 weeks from the date of consent to participate to the start of the study. 3) Patients with concomitant psychiatric or neurological disorders 4) Patients for whom MRI scans are inappropriate (e.g., those with a cardiac pacemaker, implanted defibrillator, cochlear implant, or deep brain stimulator; those with metal in their body such as a cerebral aneurysm surgical clip, artificial valve, or artificial groin; pregnant, etc.) 5) Patients with obvious cognitive decline. 6) Other persons who are judged to be ineligible by the principal investigator or co-investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Structural volume of amygdala and hippocampus | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination, facial expression test, olfactory test | — |
Countries
Japan
Contacts
Public ContactYuri Masaoka
Showa University School of Medicine Department of Physiology
Outcome results
None listed