Cerebral Infarction Traumatic Spinal Cord Injury Spinal Cord Infarction Cervical Spondylotic Myelopathy
Conditions
Interventions
Upper limb reaching exercise for 5 days
Sponsors
Kyorin University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Criteria for healthy participants: [1] Person who is between 18 and 85 years old [2] Person without history of upper motor impairments due to neurological or musculoskeletal diseases [3] Person who is right-handed Criteria for patients: [1] Person who is between 18 and 85 years old [2] Person who has been diagnosed as cerebral infarction, traumatic cervical spinal cord injury, spinal cord infarction, or cervical spondylotic myelopathy, and shows upper motor neuron sign(s) [3] Person without progression of symptoms more than 6 months after onset or decompression surgeries [4] Person who is able to reach out and grasp a 5 cm square object 30 cm away from the body
Exclusion criteria
Exclusion criteria: [1] Person who has uncontrolled medical conditions (severe heart failure, respiratory failure, diabetes mellitus, hypertension, interstitial pneumonia, kidney failure, autoimmune disease, neoplastic disease, psychiatric disease, infection, or dementia) [2] Person who needs respiratory management with ventilators [3] Person who has intracranial metallic or magnetic pieces, or pacemakers [4] Person who has implantable medical devices, person with history of seizures or epilepsy, person who takes medications, which could lower threshold for seizures (e.g. TCAs, neuroleptic agents), person who is suffering from drug abuse or withdrawal symptoms, person who is pregnant [5] Person who is considered inappropriate to become a participant by a physician [6] Person who has participated in other clinical studies within 12 weeks and has taken medication in the studies [7] Person who is participating in other clinical studies [8] Person who is a minor [9] Person without sufficient comprehension and judgement due to disease or disability even if the person is a major
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amplitudes of motor-evoked potentials at the end of intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Amplitudes of somatosensory-evoked potentials at the end of intervention Electroencephalogram-electromyogram coherence at the end of intervention Electromyogram-electromyogram coherence at the end of intervention Action Research Arm Test score at the end of intervention The Graded Redefined Assessment of Strength, Sensibility and Prehension score at the end of intervention Upper extremity motor score of the international standards for neurological classification of spinal cord injury at the end of intervention Maximum grip strength at the end of intervention Maximum pinch strength at the end of intervention Kinematics of the upper limb during prehension movements at the end of intervention Fingertip forces during prehension movements at the end of intervention | — |
Countries
Japan
Contacts
Public ContactShinya Suzuki
Kyorin University School of Medicine
Outcome results
None listed