esophageal cancer
Conditions
Interventions
radiotherapy
Sponsors
Tohoku University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. histologically proven esophageal cancer 2. Cases with T1-4a, N0-3, M0/1 lym (Japanese Esophageal Cancer Guidelines, 12th Edition) 3. Age 20 years or older and younger than 90 years old (at time of registration) 4. Performance Status (ECOG):0-1 5. Cases where surgery is inoperable or refusal is made 6. Cases where concurrent chemotherapy is difficult or refusal is made 7. Written consent has been obtained from the individual to participate in this clinical trial
Exclusion criteria
Exclusion criteria: 1. Patients with distant organ metastases other than supraclavicular or longitudinal lymph nodes. 2. Patients with a history of radiation therapy near the lesion (cases where the radiation field overlaps with this treatment). 3. Patients after esophageal cancer EMR or ESD. 4. Patients with an esophageal stent placed in the esophagus. 5. Cases with active simultaneous cancers requiring treatment other than superficial gastric cancer, prostate cancer, hypopharyngeal cancer, and primary lung cancer with only ground-glass opacity. Or cases with a disease-free period of less than 3 years, even if metachronous. 6. Patients with severe complications such as poorly controlled diabetes, collagen disease, interstitial pneumonia, and psychiatric disorders, who are not expected to tolerate this study protocol. 7. Patients with proven active infections and a fever of 38 degree or higher. 8. Patients who regularly use steroids. 9. Patients with other complications that are deemed to seriously impede the administration of treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of dysphagia 6 months after starting treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency and severity of adverse events, patient QOL and response rate | — |
Countries
Japan
Contacts
Public ContactKeiichi Jingu
Tohoku University Graduate School of Medicine Department of Radiation Oncology
Outcome results
None listed