Cardiomyopathy Muscular dystrophy Normal volunteer
Conditions
Interventions
We acquire cardiac MRI T1-mapping data at nine ventricular systolic and conventional midsystolic parameters.
Sponsors
Kobe University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Normal volunteer (1) Persons with no previous history of cardiac abnormalities such as electrocardiograms, chest radiographs or ultrasounds. (2) Persons with no symptoms of suspected heart disease. (3) Individuals without a history of diabetes or hypertension. (4) Persons who are at least 18 years of age at the time consent is obtained. (5) Persons who can obtain written consent for this study from the subject. Clinical case 1: High heart rate and arrhythmia (1) Patients who have undergone cardiac MRI examination due to suspected myocardial disease. (2) Patients with a heart rate of 80 bpm. or more at the time of examination or those with arrhythmias such as atrial fibrillation or ventricular arrhythmia. (3) Patients whose condition at the time of the examination is stable and not acute (4) Not complicated by other serious cardiac or systemic diseases (e.g. end-stage heart failure, serious renal failure) (5) The subject is at least 18 years of age (6) Who can obtain written consent for this study from the subject him/herself. Clinical case 2: Children (1) Those diagnosed with muscular dystrophy (2) Who have a resting heart rate of 100 bpm or greater (3) At least 7 years of age and less than or equal to 20 years of age (4) Subjects who are able to provide written consent for this study from themselves and their surrogates.
Exclusion criteria
Exclusion criteria: Normal volunteer People with claustrophobia, MRI non-compliant internal body metals People with psychosis or dementia requiring treatment Anyone deemed by the investigator to be unsuitable for the study. Clinical case 1: High heart rate and arrhythmia People with claustrophobia, MRI non-compliant internal body metals People with psychosis or dementia requiring treatment Anyone deemed by the investigator to be unsuitable for the study. Individuals who cannot use MRI contrast media (Gadolinium contrast media). Clinical case 2: Children People with claustrophobia, MRI non-compliant internal body metals People with psychosis or dementia requiring treatment Anyone deemed by the investigator to be unsuitable for the study. Individuals who cannot use MRI contrast media (Gadolinium contrast media).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of the image quality of T1 mapping | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in Native T1 values (pre-contrast T1 values) and Extracellular Volume Fraction (ECV) according to imaging parameters Optimal imaging parameters by arrhythmia type, heart rate and age | — |
Countries
Japan
Contacts
Public ContactHIROMI HASHIMURA
Kobe University Graduate School of Medicine Department of Radiology
Outcome results
None listed