Comparison of Multimodal Cocktail Periarticular Injection and Peripheral Nerve Block in Pain Relief After Osteotomy Around the Knee: A Prospective Randomized Controlled Trial

Comparison of Multimodal Cocktail Periarticular Injection and Peripheral Nerve Block in Pain Relief After Osteotomy Around the Knee: A Prospective Randomized Controlled Trial - Comparison of Multimodal Cocktail Periarticular Injection and Peripheral Nerve Block in Pain Relief After Osteotomy Around the Knee: A Prospective Randomized Controlled Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000054638

Enrollment

120

Registered

2024-06-13

Start date

2024-06-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Percutaneous periarticular analgesic injection including ropivacaine 0.75% 40 mL, ketoprofen 2.5 mL [50 mg], and methylprednisolone sodium succinate 0.8 mL [50 mg] just before osteotomy around the kne

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing osteotomy around the knee for knee osteoarthritis in our hospital.

Exclusion criteria

Exclusion criteria: not meeting inclusion criteria poorly controlled diabetes mellitus declined to participate

Design outcomes

Primary

Measure	Time frame
Visual Analogue Scale for postoperative pain at rest measured at 4, 8, 16, and 24 hours after surgery.	—

Secondary

Measure	Time frame
Complication Visual Analogue Scale during activity (measured at one to five days after surgery)	—

Countries

Japan

Contacts

Public ContactYoshitaka Nakao

Hyogo Medical University Department of Orthopaedic Surgery

yo-nakao@hyo-med.ac.jp0798-45-6452

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026