Improvement of hemostasis, coagulation and bleeding count with use of fresh frozen plasma for priming of the cardiopulmonary bypass circuits for cardiac surgeries in neonates and infants

Improvement of hemostasis, coagulation and bleeding count with use of fresh frozen plasma for priming of the cardiopulmonary bypass circuits for cardiac surgeries in neonates and infants - Improvement of hemostasis, coagulation and bleeding count with use of fresh frozen plasma for priming of the pediatric cardiopulmonary bypass circuits

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000054599

Enrollment

Registered

2024-06-10

Start date

2024-06-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Heart Diseases

Interventions

Use of FFP for priming of the CPB circuits

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: neonates and infants undergoing cardiac surgeries with cardiopulmonary bypass in our institution

Exclusion criteria

Exclusion criteria: cases of written informed consent not obtained from the parent of the patient

Design outcomes

Primary

Measure	Time frame
1) the platelet counts and fibrinogen levels at several time points: cessation of CPB, at cessation of modified ultrafiltration (MUF), after sternum closure and on admission in ICU (intensive care unit) 2) intraoperative transfusion volume 3) intraoperative bleeding count following the cessation of CPB 4) thrombotic complication	—

Secondary

Measure	Time frame
1) the platelet count and fibrinogen levels on the next day after the surgery 2) transfusion volume during 12 hours after the surgery 3) bleeding count during 12 hours after the surgery 4) length of stay in the ICU 5) postoperative complication and mortality	—

Countries

Japan

Contacts

Public ContactTatsuhiko Masue

Gifu Prefecturel General Medical Center Department of Anesthesiology

tatsuhikomasue@yahoo.co.jp+81-58-246-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026