Frequency and severity of postoperative bleeding after percutaneous transhepatic gallbladder drainage in patients with acute cholecystitis receiving continuous single antithrombotic drugs (A multicenter prospective study)

Frequency and severity of postoperative bleeding after percutaneous transhepatic gallbladder drainage in patients with acute cholecystitis receiving continuous single antithrombotic drugs (A multicenter prospective study) - A multicenter prospective study of the impact of single antithrombotic drug continuation on postoperative bleeding after PTGBD

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000054582

Enrollment

500

Registered

2024-07-01

Start date

2024-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with indication of PTGBD for acute cholecystitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients over 18 years-old at the time of entry Patients with indication of PTGBD for acute cholecystitis Patients with no antithrombotic drug use or receiving a single antithrombotic drug before PTGBD Patients who have provided written consent for participation

Exclusion criteria

Exclusion criteria: Patients receiving multiple antithrombotic drugs Patients who cannot consent to participate Patients judged by study investigator/sub-investigators as inappropriate ones

Design outcomes

Primary

Measure	Time frame
Frequency and severity of bleeding after PTGBD in patients with acute cholecystitis according to the use of the antithrombotic drug	—

Secondary

Measure	Time frame
1. The factors associated with whole bleeding and severe bleeding after PTGBD 2. The frequency of postoperative bleeding for each antithrombotic drug and comparison of bleeding rates for antiplatelets and anticoagulants 3. Relationship between frequency of patients receiving appropriate dosage of DOACs according to renal function and bleeding rates after PTGBD in patients receiving DOACs	—

Countries

Japan

Contacts

Public ContactTeppei Yoshioka

Osaka University Graduate School of medicine Gastroenterology and Hepatology

teyoshioka@gh.med.osaka-u.ac.jp0668793621

Outcome results