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Do two differnt neuromodulators improve upper limb paralysis of stroke patients in acute phase?

Effects of combined neuromodulations on upper limb paralysis of stroke patients in acute phase - Effects of combined neuromodulation on upper limb paralysis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000054562
Enrollment
54
Registered
2024-08-01
Start date
2024-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute phase of stroke

Interventions

The intervention group receive occupational therapy using a combination of transcranial direct current stimulation and repetitive peripheral magnetic stimulation. Occupational regular therapy is per

Sponsors

Saitama Medical University General Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients diagnosed with stroke (cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, cerebrovascular malformation) 2) hospitalized adults within one weeks of stroke 3) first-ever, severe to moderate upper limb paralysis (Brunnstrom Stage: upper limb II-IV/fingers II-IV, Stroke impairment assessment set: knee-mouth test range 1-3 finger function test 1a-3) 4) level of consciousness is 1 digit on the Japan Coma Scale 5) adequate cognition to participate (target patients who can understand explanations) 6) medically stable

Exclusion criteria

Exclusion criteria: 1) past history of convulsive seizures 2) past history of neuropsychiatric disorders 3) implanted stimulator (such as cardiac pacemaker) 4) past history of serious arrhythmia or heart failure 5) Patients with muscle disease

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer upper limb assessment

Secondary

MeasureTime frame
Wolf motor function test Barthel index Left and right grip strength/pinch strength

Countries

Japan

Contacts

Public ContactHIROYUKI KURIHARA

Saitama Medical University General Medical Center Department of Rehabilitation medicine

kuri610@saitama-med.ac.jp049-228-3529

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026