Chronic kidney disease End stage kidney disease (ESKD)
Conditions
Interventions
None listed
Sponsors
Nihon University Itabashi Hospital
Akabanechuo hospital fuzoku Clinic Shikiekimae Clinic. Asakadaitoseki Clinic Yujin Clinic. Yujinoizumigakuen Clinic. YujinKamishakujii Clinic. Toshima chou Hospital. Ishin Clinic.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients on hemodialysis Patients over 20 years old Patients who agreed to participate in the study
Exclusion criteria
Exclusion criteria: Patients who refused to participate in this study. Patients judged by the principal investigator to be inappropriate as research subjects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In patients on hemodialysis, hazard ratio and odds ratio of the baseline hepcidin and ESKD related protein concentration for the onset of future cardiovascular events. | — |
Secondary
| Measure | Time frame |
|---|---|
| Optimal cutoff value, sensitivity, specificity, positive predictive value, negative predictive value for cardiovascular events. Optimal cutoff value for blood hepcidin and ESKD-related protein levels in ESA hyporesponsiveness. Sensitivity, specificity, positive predictive value, negative predictive value in the diagnosis of ESA hyporesponsiveness. Comparison of diagnostic ability of blood hepcidin concentration and erythropoietin resistance index (ERI). Rate of change in hepcidin and ESKD-related proteins before and after administration of ESAs. | — |
Countries
Japan
Contacts
Public ContactTakashi Maruyama
Nihon University Itabashi Hospital Internal medicine, division of Nephrology, Hypertension and Endocrinology
Outcome results
None listed