Effect of bolus administration of remimazolam during induction of general anaesthesia on hemodynamic variables in patients undergoing hip replacement and endoscopic sinus surgery.

Effect of bolus administration of remimazolam during induction of general anaesthesia on hemodynamic variables in patients undergoing hip replacement and endoscopic sinus surgery. - Bolus administration of remimazolam and hemodynamic variables.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000054501

Enrollment

Registered

2024-05-30

Start date

2023-11-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis and sinusitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 20 years and less than 80 years between 1 September 2023 and 31 March 2025 with an American Society of Anaesthesiologists general status classification (ASA-PS)1 or 2 for planned hip replacement and endoscopic sinus surgery.

Exclusion criteria

Exclusion criteria: Emergency surgery, history of cardiovascular disease, pregnancy, history of severe liver dysfunction, on dialysis, history of neurological disease, history of drug hypersensitivity, history of severe lipid metabolism disorders, BMI >30 kg/m2.

Design outcomes

Primary

Measure	Time frame
Maximum change in mean blood pressure immediately before remimazolam administration and every minute up to 5 minutes after administration	—

Countries

Japan

Contacts

Public ContactTOMOHARU SHAKUO

Showa University Northern Yokohama Hospital Department of Anesthesiology

shakuo@med.showa-u.ac.jp0459497000

Outcome results