None listed
Conditions
Interventions
None listed
Sponsors
Kao Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Men and women who are between 50 and 89 years of age at the time of obtaining the informed consent. 2.Persons who are not currently undergoing treatment for any serious disease 3.Persons who are living independently (e.g., those who can shop and pay bills alone and does not need assistance with daily activities) 4.Persons who are able to come to the designated facility on the scheduled visit date 5.Persons who are fully understand the purpose and content of this examination.
Exclusion criteria
Exclusion criteria: 1.Person who have been diagnosed with dementia and are taking dementia treatment medication. 2.Persons who have been diagnosed with depression and are taking antidepressant medication. 3.Persons who have undergone treatment, hospitalization, or surgery for head injuries such as stroke or subarachnoid hemorrhage. 4.Persons who have liver, kidney, heart, respiratory, endocrine, metabolic, neurological, consciousness disorders, or other diseases. 5.Persons with a history of neurodegenerative diseases, cardiovascular diseases, or thyroid disorders. 6.Persons who have had a serious illness (such as cancer) within the past 5 years. 7.Persons with diabetes (as defined by the Japan Diabetes Society). 8.Persons who have contracted infectious diseases (syphilis, HIV, HCV, HBs antigen positive). 9.Persons who are taking medication that may affect cognitive function (antipsychotics, anxiolytics, antidepressants, etc.). 10.Persons who consume excessive alcohol (consuming an average of 60g or more of pure alcohol per day, equivalent to 3 bottles of beer, 3 small bottles of sake, or 300ml of 25% shochu). 11.Persons who smoke excessively (smoking 20 or more cigarettes per day). 12.Person who tested positive for the COVID-19 antigen test at the time of the visit. 13.Persons who have had fever, respiratory symptoms, or has had close contact with a confirmed case of COVID-19 within the past 2 weeks. 14.Any other individuals deemed unsuitable for participation in this study by the study's principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of the relationship between cognitive function and blood amino acids | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of the relationship between cognitive function and other blood factors (polyamines, vitamins, hematology and biochemistry tests) and urinary factors (amino acids, polyamines, vitamins) and construction of statistical models. | — |
Countries
Japan
Contacts
Public ContactKoichi Misawa
Kao Corporation Biological Science Research Lab.
Outcome results
None listed