Breast cancer patients with posotive lymph node metastasis who need neoadjuvant chemotherapy
Conditions
Interventions
None listed
Sponsors
Gifu University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Primary breast cancer with pathologically node-positive 2)cT0-T4, cN1-3, M0(cStage IIA-IIIC) 3)patient who need NAC 4)more than 20yo, male and female 5)PS 0-2 6)available for insertion of the intra-tumoral marker 7)agree to participate in this trial
Exclusion criteria
Exclusion criteria: 1)imposible to insert intra-tumoal marker 2)not agreed to perform TAS&Ax 3)impossible to perform NAC becauseof medical problem, HBV/HVC-positive case in acceptable with anappropriate treatment 4)pregnant 5)mental disorder 6) decision not appropriate to join the trial by PI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection rate of the marker in intra-tumoal tumror by virtual sonography aftr neoadjuvant chemotherapy | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Number of lymph nodes in TAS & Ax specimen 2) False positive rate of positive lymph nods in TAS & Ax specimen 3) Radiological detection rate of tje intra-tumoal tumor by US-US fusion, US-CT fusion image 4) Time till detection of the intra-tumoal tumor by virtual somnography 5) Adverse events 6)Radiological change of the marker located in the positive lymph node | — |
Countries
Japan
Contacts
Public ContactManabu Futamura
Department of breast surgery Gifu University Graduate school of Medicine Department of breast surgery Gifu University Graduate school of Medicine
Outcome results
None listed