Cellular Dynamics Associated with Crohn's Disease Strictures: An Examination of the Impact of Biologic Agents

Clinical Trial on the Impact of Biologic Agents on Crohn's Disease Strictures - Biologic Impact on Crohn's Stricture Trial (BICST)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000054449

Enrollment

Registered

2024-05-25

Start date

2024-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn&#39

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Crohn's disease who are either outpatient or inpatient at our institution. Patients aged 18 to under 80 years at the time of enrollment. Patients who have provided written informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: Patients with any of the following history or complications: Intestinal tuberculosis Nonspecific multiple small bowel ulceration NSAIDs-induced ulcer Cases where the treatment medication has been changed within one year prior to tissue collection (e.g., from Ustekinumab to Infliximab) Cases using steroids within one year prior to tissue collection Any other patients whom the principal investigator or attending physician deems unsuitable for safe participation in the study.

Design outcomes

Primary

Measure	Time frame
Gene Expression Patterns of Fibroblasts in Strictures	—

Countries

Japan

Contacts

Public ContactYUKI HIRATA

Osaka Medical and Pharmaceutical University Second department of Internal Medicine

yuki.hirata.ln@ompu.ac.jp0726831221

Outcome results