Impact of lymphatic and venous invasion patterns on postoperative prognosis and distant metastasis in esophageal squamous cell carcinoma following preoperative chemotherapy

Impact of lymphatic and venous invasion patterns on postoperative prognosis and distant metastasis in esophageal squamous cell carcinoma following preoperative chemotherapy - Impact of lymphatic and venous invasion patterns on postoperative prognosis in ESCC after NAC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000054427

Enrollment

400

Registered

2024-12-01

Start date

2024-05-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal squamous cell carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with ESCC underwent subtotal esophagectomy with digestive tract reconstruction

Exclusion criteria

Exclusion criteria: 1 Surgery alone 2 Neoadjuvant chemotherapy (NAC) regimen other than cisplatin and 5-fluorouracil (CF regimen) or docetaxel, cisplatin, and 5-fluorouracil (DCF regimen) 3 Preoperative chemoradiotherapy 4 R1 or R2 resection 5 unknown recurrence pattern

Design outcomes

Primary

Measure	Time frame
Overall survival (OS), Recurrence-free survival (RFS), Distant metastasis-free survival (DMFS)	—

Countries

Japan

Contacts

Public ContactTakeo Fujita

National Cancer Center Hospital East Division of Esophageal Surgery

takfujit@east.ncc.go.jp04-71331-111

Outcome results