Molecular characterization of root resorption using Osteopontin in different intrusion methods

Molecular characterization of root resorption using Osteopontin in different intrusion methods - Molecular characterization of root resorption in different intrusion methods

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000054416

Enrollment

Registered

2024-05-16

Start date

2022-08-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Root resorption in deep bite patients

Interventions

Anterior bite turbos Reverse curve of spee archwires

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -Fixed orthodontic treatment with non-extraction of teeth -Increased overbite suggestive of deepbite -Average growth pattern and mild skeletal discrepancy -No missing or extracted tooth -No history of anti-microbial therapy -No use of anti inflammatory drugs within the month preceding study. -Healthy periodontal tissues with generalised probing depth with minimal bleeding. -No radiographic evidence of periodontal bone loss.

Exclusion criteria

Exclusion criteria: -Subjects which are periodontally compromised. -Patients with increased overjet -Patients with previous orthodontic treatment -Poor oral hygiene -Pregnant or lactating females

Design outcomes

Primary

Measure	Time frame
The study was conducted with the following objectives: 1.To examine the levels for Ostepontin in GCF for root resorption in both treatment techniques through ELISA at different time intervals (prior to orthodontic treatment and after the levelling and alignment stage). 2. To examine and compare root resorption between two groups using periapical radiography (along with grid to measure root resorption) at two different time intervals.	—

Measure

Time frame

The study was conducted with the following objectives: 1.To examine the levels for Ostepontin in GCF for root resorption in both treatment techniques through ELISA at different time intervals (prior to orthodontic treatment and after the levelling and alignment stage). 2. To examine and compare root resorption between two groups using periapical radiography (along with grid to measure root resorption) at two different time intervals.

—

Countries

Asia(except Japan)

Contacts

Public ContactPrince Bedi

I.T.S- CENTRE FOR DENTAL STUDIES AND RESEARCH, MURAGNAGAR,GHAZIABAD DEPARTMENT OF ORTHODONTICS AND DENTOFACIAL ORTHOPAEDICS

pbedi570@gmail.com9818705650

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026