primary lung cancer, metastatic lung cancer
Conditions
Interventions
To perform stereotactic MR-guided online adaptive radiosurgery for small lung cancer
Sponsors
Tohoku University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Pathologically or clinically diagnosed primary lung cancer or solitary metastatic lung cancer: lack of or controlled lymph node metastasis, pulmonary metastasis, and other distant metastases 2.Lung tumor was 5 cm or less in diameter and was not attached to chest wall 3.Tumor was not adjacent organ at risk: trachea, main~lobar bronchus, heart, spinal cord, brachial plexus, esophagus, stomach 4.Forced expiratory volume 1.0:700 mL <= 5.Performance status(ECOG):0-2 6.Medically inoperable or patient who refused surgery 7.Written informed consent
Exclusion criteria
Exclusion criteria: 1.Patients with severe complications such as uncontrolled diabetes, collagen disease, heart disease, lung disease, kidney disease, and mental illness 2.Receiving home oxygen therapy 3.Pregnant, lactating, or likelihood of pregnancy 4.Active infectious disease 5.History of radiation therapy that may overlap with the current treatment 6.Presence of obvious interstitial shadows on CT images 7.Cases with pacemakers, implanted defibrillators, or other internal metals incompatible with MRI 8.Claustrophobia preventing MRI examination 9.Patients with psychiatric illness or symptoms making participation in the study difficult to assess
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| One-year local control and incidences of rib fracture | — |
Secondary
| Measure | Time frame |
|---|---|
| One-year overall survival time One-year progression free survival Incidences of serious adverse events | — |
Countries
Japan
Contacts
Public ContactTakaya Yamamoto
Tohoku University Hospital Department of Radiation Oncology
Outcome results
None listed