Stroke
Conditions
Interventions
Interventions (BMI group): Botulinum toxin plus BMI training. In BMI group, patients are provided with training using electroencephalogram-induced orthoses and electrical stimulators. Daily trainin
Sponsors
Nagoya City University Rehabilitation Hospital
LIFESCAPES Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) age between 20 to 80 years 2) time since stroke onset longer than 180 days 3) inability to extend the paretic finger after first stroke (Stroke Impairment Assessment Set (SIAS) < IB) 4) Modified Ashworth Scale (MAS) of Hand flexor muscle >= 1+ 5) Patients who are hospitalized after botulinum toxin to the hand flexor muscle
Exclusion criteria
Exclusion criteria: A patient who falls under the following; 1) subarachnoid hemorrhage 2) recurrent stroke 3) other neuromuscular disorders 4) severe spasticity or contracture of the fingers and are unable to extend or close the fingers passively (MAS >= 3) 5) phenomenon of forced grasp, apraxia, and unilateral spatial neglect 6) sever mental disorder (affects concentration and continuation of training) 7) cognitive deficits as determined by Mini mental state examination <= 23 8) significant hearing or visual impairment 9) Unable to attach the myoelectric electrode due to skin disease or difficult to wear the hand electric orthosis 10) serious hepatic, renal, cardiovascular, or respiratory disorders 11) Uncured malignancy 12) no history of seizures within the past 2 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment(FMA) hand scale, Modified Ashworth Scale(MAS) of Hand flexor muscle | — |
Secondary
| Measure | Time frame |
|---|---|
| FMA upper limb score/sensory score for upper limb, Action Research Arm Test(ARAT), Motor Activity Log(MAL), Disability Assessment Scale(DAS), Visual Analogue Scale(VAS) for pain, Stroke Impact Scale(SIS)hand scale, Electroencephalography, surface electromyography, and evoked electromyography at rest and during attempts at finger extension | — |
Countries
Japan
Contacts
Public ContactNaoya Anmoto
Nagoya City University Rehabilitation Hospital Division of Occupational Therapy, Department of Rehabilitation Medicine
Outcome results
None listed