An exploratory study on the relationship between protein intake in elderly individuals living in a community and plasma albumin redox state, urinary taurine, and urinary trimethylamine N-oxide.

An exploratory study on the relationship between protein intake in elderly individuals living in a community and plasma albumin redox state, urinary taurine, and urinary trimethylamine N-oxide. - An exploratory study on the relationship between protein intake in elderly individuals living in a community and plasma albumin redox state, urinary taurine, and urinary trimethylamine N-oxide.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000054344

Enrollment

Registered

2024-05-11

Start date

2024-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition

Interventions

Intake of protein foods

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Individuals who understand and agree with the purpose of this study. Individuals who have not been diagnosed with dementia. Individuals with 20 or more functional teeth. Individuals who do not have impaired swallowing function.

Exclusion criteria

Exclusion criteria: Individuals with deficiencies in the 2011 cohort data from the "Otassha-kenshin" health checkups conducted in the fiscal year 2023. Individuals with severe systemic illnesses (including past medical history) such as cancer, liver or kidney diseases, digestive disorders, heart diseases, diabetes, neuromuscular disorders, or cerebrovascular disorders. Individuals using a cardiac pacemaker. Individuals with serum creatinine levels above 1.2 mg/dL for males or above 1.0 mg/dL for females (based on the 2023 "Otassha-kenshin" health checkup results). Individuals currently participating in or within 4 weeks of completing participation in other intervention studies, or individuals planning to participate in such studies. Individuals unable to chew or swallow food. Other individuals deemed ineligible for inclusion as research subjects by the judgment of a physician or dentist (research collaborator).

Design outcomes

Primary

Measure	Time frame
Changes in albumin oxidative-reduction balance, urinary taurine, and urinary TMAO levels, along with the consumption status of commercially available protein-fortified foods (3months)	—

Countries

Japan

Contacts

Public ContactMisato Hayakawa

Tokyo Metropolitan Institute for Geriatrics and Gerontology Research Team for Promoting Independence and Mental Health

kemotokawa@gmail.com03-3964-3241

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026