none
Conditions
Interventions
None listed
Sponsors
Keio University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A. Smoking cessation clinic patients: (1) Japanese nationals 20 years of age or older. (2) Those who have started their first visit to a smoking cessation clinic. (3) Have given written consent to participate in this study. B. Healthy volunteers: (1) Japanese who are 20 years of age or older (2) Non-smokers (3) Have given written consent to participate in this study.
Exclusion criteria
Exclusion criteria: A. Smoking cessation clinic patients: (1) Patients who have already quit smoking at the time of their first visit to a smoking cessation clinic (2) Patients with a history of intestinal tract surgery (3) Persons deemed inappropriate by the principal investigator or subinvestigator to conduct this study. B. Healthy volunteers: (1) Those who have a history of intestinal tract surgery (2) Persons with a history of smoking in the past (3) Persons who are deemed inappropriate by the principal investigator or subinvestigator to conduct this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comprehensive analysis of the bacterial flora in stools will be performed before and after smoking cessation and compared. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of blood and stool metabolites, systemic inflammation, and in vivo characteristics of the intestinal microflora in the stool, measurement of salivary cotinine to assess nicotine in the body, and assessment of living conditions using a questionnaire will be conducted before and after smoking cessation and compared. | — |
Countries
Japan
Contacts
Public ContactShotaro Chubachi
Keio University School of Medicine Division of Pulmonary Medicine
Outcome results
None listed