A multi-institutional prospective observational study of incidence and risk factors for the development of osteosarcopenia in patients with unresectable pancreatic cancer receiving chemotherapy

A multi-institutional prospective observational study of incidence and risk factors for the development of osteosarcopenia in patients with unresectable pancreatic cancer receiving chemotherapy - An observational study of incidence and risk factors for the development of osteosarcopenia in patients with unresectable pancreatic cancer receiving chemotherapy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000054288

Enrollment

150

Registered

2024-05-01

Start date

2024-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for chemotherapy for unresectable pancreatic invasive ductal adenocarcinoma. Patients with pathologically diagnosed pancreatic invasive ductal adenocarcinoma. Patients over 18 years old. Informed consent obtained

Exclusion criteria

Exclusion criteria: Patients undergoing chemotherapy for pancreatic cancer prior to obtaining informed consent. Patients deemed ineligible for the study

Design outcomes

Primary

Measure	Time frame
Cumulative incidence of osteosarcopenia up to 12 months	—

Secondary

Measure	Time frame
The incidence of osteosarcopenia, the incidence of bone-related adverse events, the incidence of osteoporosis, the incidence of bone loss, the incidence of sarcopenia, the incidence of low trabecular bone score, overall survival, chemotherapy-induced adverse events, relative dose intensity, factors related to the incidence of osteosarcopenia (before chemotherapy, 6 and 12 months)	—

Countries

Japan

Contacts

Public ContactSho Ishikawa

Ehime University Graduate School of Medicine Department of Gastroenterology and Metabology

ishikawa.sho.nu@ehime-u.ac.jp0899645111

Outcome results