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Association between delivery type and Kawasaki disease onset

Association between delivery type and Kawasaki disease onset - Association between delivery type and Kawasaki disease onset

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000054284
Enrollment
70000
Registered
2024-04-30
Start date
2005-01-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kawasaki disease

Interventions

None listed

Sponsors

Chiba Cancer Center Research Institute
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Information on the children delivered via CS or VD and their mothers was collected from all periods in the database. CS was performed using a procedure detected using Japanese medical procedure codes.Herein, the primary outcome was defined as KD occurrence based on specific criteria. Specifically, we included patients diagnosed with KD (ICD-10 code M303) who had received intravenous immunoglobulin treatment.

Exclusion criteria

Exclusion criteria: Cases labeled as suspected were excluded, whereas those with atypical KD were included. Considering the importance of an accurate diagnosis in this study, we excluded patients more than 6 years of age because this is not the typical age of KD onset, and distinguishing KD from other diseases in this age group is challenging.

Design outcomes

Primary

MeasureTime frame
Patients with KD were identified from the source population. Subsequently, in every case, we randomly selected controls with no KD history based on a risk-set sampling technique. Each patient was matched to four controls of the same sex, age, and registration time in the database. We subsequently examined the association between the delivery type and KD onset using multivariate conditional logistic regression analysis.We defined the primary outcome as KD, based on specific criteria.

Countries

Japan

Contacts

Public ContactTakanori Suzuki

Fujita health university Pediatrics

takanori-s@axel.ocn.ne.jp09025786815

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026