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Search for an optimal equation for estimating glomerular filtration rate (GFR) in Japanese patients with digestive malignancies: Considering muscle mass

Search for an optimal equation for estimating glomerular filtration rate (GFR) in Japanese patients with digestive malignancies: Considering muscle mass - Search for an optimal equation for estimating glomerular filtration rate (GFR) in Japanese patients with digestive malignancies: Considering muscle mass

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000054261
Enrollment
100
Registered
2024-04-30
Start date
2024-01-16
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unresectable digestive malignancies

Interventions

None listed

Sponsors

Hokkaido university hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Over 18 years of age 2. Presence of unresectable gastrointestinal malignancies 3. Written informed consent

Exclusion criteria

Exclusion criteria: 1. History of hypersensitivity to inulin. 2. Those who are taking probucol, tocopherol acetate, or vitamin preparations and are unable to take a break from taking them on the day before and on the day of inulin clearance measurement. 3. The patient is taking methyldopa orally. 4. eGFR calculated using the Japanese Society of Nephrology's estimation formula is less than 15 mL/min/1.73m2. 5. Subjects who are taking steroids and cannot stop taking them for 14 days before measuring inulin clearance. 6. Other individuals who are judged by the research director or co-researcher to be inappropriate as research subjects.

Design outcomes

Primary

MeasureTime frame
Correlation between inulin clearance and eGFR calculated using various estimation equations

Secondary

MeasureTime frame
Clinical characteristics of cases with significant discrepancies between inulin clearance and eCcr calculated by the CG equation

Countries

Japan

Contacts

Public ContactShiho Kaneko

Hokkaido University Hospital Division of Cancer Center

kaneko.shiho.s8@elms.hokudai.ac.jp0117161161

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026