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Comparison of dexmedetomidine and magnesium sulphate in laparoscopic cholecystectomy

Comparative Evaluation of effects of Dexmedetomidine and Magnesium Sulphate on Haemodynamic Parameters during Laparoscopic Cholecystectomy under General Anaesthesia - DEXMED, LC, MG

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000054257
Enrollment
45
Registered
2024-04-25
Start date
2014-01-08
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Symptomatic cholelithiasis

Interventions

Patients were given 100ml NS 0.9% IV (group NS, n=15) over a period of 10 minutes in double blinded manner after induction of anaesthesia but before creation of pneumoperitoneum Patients were given D

Sponsors

University College of Medical Sciences AND GTB Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ASA (American Society of Ananesthesiologist) physical status-1,aged between 18-60 years of either sex undergoing elective laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Patients with history of cardiovascular disease, endocrine disease like uncontrolled diabetes mellitus, thyroid disorder, compromised renal, hepatic, neuronal functions, pregnant or lactating females or any patient taking drugs affecting cardiovascular parameters . Conversion of laparoscopic to open cholecystectomy, excessive internal bleeding leading to hypotension or requiring blood transfusion or duration of pneumoperitoneum more than 2 hours

Design outcomes

Primary

MeasureTime frame
To study and compare the effects of intravenous single dose dexmedetomidine and magnesium sulphate on haemodynamic parameters in patients undergoing elective laparoscopic cholecystectomy under general anaesthesia

Secondary

MeasureTime frame
ioflurane concentration, pain, post operative nausea and vomiting, sedation

Countries

Asia(except Japan)

Contacts

Public ContactANKITA KAASAT

Ananta Institute of Medical Sciences and Research Centre DEPARTMENT OF ANAESTHESIA AND CRITICAL CARE

ankitakaasat@gmail.com6361854732

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026