Effect of thoracic fluid content on electrical impedance tomography (EIT) measurements

Effect of thoracic fluid content on electrical impedance tomography (EIT) measurements - Effect of thoracic fluid content on electrical impedance tomography (EIT) measurements

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000054238

Enrollment

Registered

2024-04-23

Start date

2024-04-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non

Interventions

1. measurement will be performed in the anesthesiologist&#39

s office 2. The time required is about 1 hour (including breaks). (including a break) 3. recruitment of subjects will be open to the public. 4. recruitment will be open to healthy healthcare pro

s office and surrounding corridors. 5. a supine healthy adult will be fitted with an electrical impedance tomography (EIT) measurement belt

6. a flow sensor will be connected to the EIT belt

7. the EIT belt will be attached to the anesthesiologist&#39

s chest A face mask with a flow sensor attached will be placed on the subject, and spontaneous breathing will be induced to simultaneously measure respiratory parameters such as airway pressure, flow

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) ASA-PS (American Society of. Anesthesiologists physical status) 1 or 2. (2) Persons who have given their written consent to participate in the study.

Exclusion criteria

Exclusion criteria: Patients with pre-existing respiratory disease. Patients with pre-existing cardiovascular disease. Patients with pre-existing neuromuscular disease.

Design outcomes

Primary

Measure	Time frame
This study is a prospective, before-and-after comparative study. The primary objective of this study was to verify whether the impedance values measured by EIT change accordingly when the amount of fluid in the thoracic cavity is increased. Interventions to increase intrathoracic fluid content will include generating negative pressure in the thoracic cavity through a combination of inspiratory effort and flow restriction, and through positional changes (standing, supine, and elevated lower extremities). After measuring baseline parameters (ventilatory output, airway pressure, flow, resistance, and impedance using EIT) with a ventilometer, techniques to increase intrapleural fluid volume (increasing intrapleural negative pressure with inspiratory effort and flow restriction, or changing body position) are performed on the subject, and baseline parameters are measured as in the baseline procedure. parameters as at baseline. Pre- and post-intervention comparisons will test the hypothesis that increased intrathoracic fluid content will increase the impedance value measured by EIT. Corresponding t-tests or Wilcoxon's signed rank sum test will be used for pre- and post-intervention comparisons of parameters, and correlation analysis will be used to examine the relationship between intrathoracic pressure (substituted by airway pressure due to the difficulty of directly measuring it) and impedance values.	—

Measure

Time frame

This study is a prospective, before-and-after comparative study. The primary objective of this study was to verify whether the impedance values measured by EIT change accordingly when the amount of fluid in the thoracic cavity is increased. Interventions to increase intrathoracic fluid content will include generating negative pressure in the thoracic cavity through a combination of inspiratory effort and flow restriction, and through positional changes (standing, supine, and elevated lower extremities). After measuring baseline parameters (ventilatory output, airway pressure, flow, resistance, and impedance using EIT) with a ventilometer, techniques to increase intrapleural fluid volume (increasing intrapleural negative pressure with inspiratory effort and flow restriction, or changing body position) are performed on the subject, and baseline parameters are measured as in the baseline procedure. parameters as at baseline. Pre- and post-intervention comparisons will test the hypothesis that increased intrathoracic fluid content will increase the impedance value measured by EIT. Corresponding t-tests or Wilcoxon's signed rank sum test will be used for pre- and post-intervention comparisons of parameters, and correlation analysis will be used to examine the relationship between intrathoracic pressure (substituted by airway pressure due to the difficulty of directly measuring it) and impedance values.

—

Countries

Japan

Contacts

Public ContactKazuhiro Takahashi

Tohoku University Graduate School of Medicine Department of Anesthesiology and Perioperative Medicine

takahashi.kazuhiro@med.tohoku.ac.jp022-717-7321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026