Skip to content

Study on Hemodynamic Analysis of the Portal Venous Region Using 3D cine Phase Contrast MRI (4D Flow MRI) and Its Association with Prognosis and Treatment Efficacy

Study on Hemodynamic Analysis of the Portal Venous Region Using 3D cine Phase Contrast MRI (4D Flow MRI) and Its Association with Prognosis and Treatment Efficacy - Portal Venous 4D Flow MRI Analysis Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000054232
Enrollment
216
Registered
2024-07-01
Start date
2024-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver diseases in general

Interventions

None listed

Sponsors

Nagoya University Graduate School of Medicine Department of Fundamental Development for Advanced Low Invasive Diagnostic Imaging Ryota Hyodo
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adult patients who are capable of understanding the contents of the research. 2. Patients with various degrees of portosystemic shunt and a control group of patients without portosystemic shunt. All are scheduled for abdominal contrast-enhanced MRI at our hospital for routine clinical purposes, such as the diagnosis and assessment of hepatocellular carcinoma, hepatic hemangiomas, metastatic liver tumors, shunts, and other tumors. 3. Patients scheduled for chemotherapy for primary liver tumors or metastatic liver tumors. All are regularly scheduled for abdominal contrast-enhanced MRI for routine clinical evaluation of primary or metastatic tumors. 4. Additionally, individuals who participated in the studies "Research on human vascular hemodynamics analysis using three-dimensional cine phase-contrast magnetic resonance imaging method (jRCTs041180157)" and "Hemodynamic study of the portal venous region using 3D cine phase contrast MRI(4D Flow MRI)(Approval number 2023-0140)" and have consented to the secondary use of their data for future research (must meet the criteria outlined in 2 or 3 above).

Exclusion criteria

Exclusion criteria: Individuals who have declined to participate in the study, those with contraindications for MRI such as metallic implants in the body or claustrophobia, and those who find it difficult to remain still for about an hour.

Design outcomes

Primary

MeasureTime frame
1. Survival outcomes 2. Reduction in liver tumor size (according to RECIST criteria)

Countries

Japan

Contacts

Public ContactRyota Hyodo

Nagoya University Graduate School of Medicine Department of Fundamental Development for Advanced Low Invasive Diagnostic Imaging

hyodo.ryota.w3@f.mail.nagoya-u.ac.jp0527442327

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026