Genetic analysis in platelets of patients with infectious diseases

Comprehensive analysis of platelet RNA expression profiles in sepsis - Comprehensive analysis of platelet RNA expression profiles in sepsis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000054197

Enrollment

150

Registered

2024-04-22

Start date

2024-04-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. A person who enters the intensive care unit of this hospital (regardless of the condition that leads to the admission) 2. A person who receives a thorough explanation of his participation in this study, and gives his (or his surrogate's) free and voluntary written consent based on a thorough understanding of the situation.

Exclusion criteria

Exclusion criteria: 1. A patient with significant anemia 2. A patient who takes antiplatelet or anticoagulant medication 3. Other person who is deemed by the principal investigator to be inappropriate to participate in the study

Design outcomes

Primary

Measure	Time frame
Differences in platelet mRNA and miRNA expression between septic and non-septic patients	—

Secondary

Measure	Time frame
1.Differences in platelet mRNA and miRNA expression between septic patients with diabetes mellitus and those without diabetes mellitus 2.Expression levels of related proteins	—

Countries

Japan

Contacts

Public ContactKei Houri

Kindai University Faculty of Medicine Deprtment of Anesthesiology

labo.anesth.kindai@gmail.com072-366-0221

Outcome results