Healthy adults (those who are not suffering from any diseases, excluding those(/individuals) under 18 years old, pregnant women, and lactating women)
Conditions
Interventions
None listed
Sponsors
FANCL Corporation
Professor Hiroharu Kamioka, Tokyo University of Agriculture
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: P-Participant: Participant The subjects were healthy volunteers (excluding those under 18, pregnant women, and lactating women, who were not suffering from any diseases). I-Intervention: Intervention (food) characteristics The intervention condition was defined as the intake of foods containing "lutein, zeaxanthin", with unlimited intake quantities, intake period, and follow-up period. Studies involving interventions with a 5:1 ratio of "lutein, zeaxanthin" will be included to ensure equivalence with the final product. C-Comparison: Comparison group A comparison was made among one receiving a placebo, another serving as a control group in which food was substituted with food that does not contain "lutein , zeaxanthin" and group with no intervention. O-Outcome: Evaluation items Main outcomes: Macular Pigment Optical Density(MPOD) Secondary outcomes: Protection from light stimulation, Contrast sensitivity S-Study design: Research design The research designs used in the literature were randomized parallel group controlled trials (RCTPs), randomized crossover trials (RCTCOs), and quasi-randomized controlled trials (quasi-RCTs). In addition, the languages of presentation were documents written in Japanese and English. As a general rule, the presentation format will be an original paper, and papers in the form of short reports or summaries will also be accepted if the content can be specified. Abstracts of academic conference presentations (conference minutes) were excluded because their descriptive content was considered insufficient. There was no question as to whether or not the journal in which the article was published had been peer-reviewed. To avoid publication bias, we also included studies with results published in clinical trial registry databases. Regarding gray literature, we decided to use doctoral theses, reports from government agencies, think tanks, etc. whose detailed contents could be identified.
Exclusion criteria
Exclusion criteria: The literature which does not meet the key inclusion criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Macular Pigment Optical Density(MPOD) | — |
Secondary
| Measure | Time frame |
|---|---|
| Protection from light stimulation, Contrast sensitivity | — |
Countries
Japan
Contacts
Public ContactMasakazu Katsu
FANCL Corporation Functional Food Research Institute
Outcome results
None listed