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Computed Tomography Perfusion Tissue Time to Maximum Predict Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage

Computed Tomography Perfusion Tissue Time to Maximum Predict Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage - Computed Tomography Perfusion Tissue Time to Maximum Predict Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000054121
Enrollment
60
Registered
2024-04-11
Start date
2024-03-27
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subarachnoid hemorrhage

Interventions

None listed

Sponsors

Japanese Red Cross Kumamoto Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients with subarachnoid hemorrhage who underwent endovascular treatment or craniotomy at Japanese Red Cross Kumamoto Hospital during the 2-year period from May 12, 2021 to May 11, 2023

Exclusion criteria

Exclusion criteria: Exclusions were made for individuals with a fifth grade of the World Federation of Neurosurgical Societies (WFNS) Grade and those who had undergone parent artery occlusion, as their inclusion might compromise the accuracy of cerebral perfusion assessment. Within our institution, all patients afflicted with aSAH underwent CT perfusion imaging between days 8 and 12 following the onset of SAH. Following day 14 post-SAH, either CT or MRI was performed, with the date of SAH onset denoted as day 0. Nevertheless, patients who, for any conceivable reason, did not undergo CT perfusion imaging at any point during their clinical trajectory or did not undergo evaluation for DCI, were subject to exclusion.

Design outcomes

Primary

MeasureTime frame
We defined delayed cerebral ischemia as a new cerebral infarction occurring 3-18 days after the onset of subarachnoid hemorrhage. The primary endpoint was the ability of RAPID Software's time to maximam analysis values using perfusion CT performed after 8-12 days of onset to predict the development of delayed cerebral ischemia.

Countries

Japan

Contacts

Public ContactTsuboki Shimpei

Kameda Medical Center Department of Neuroendovascular surgery

si.tsuboki@gmail.com04-7092-2211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026