hereditary cancers
Conditions
Interventions
In this study, blood samples will be collected mainly in conjunction with genetic testing and, less frequently, saliva and other body fluids, skin, oral mucosa, etc. will be collected. In the case of
Sponsors
The Cancer Institute Hospital of JFCR
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Samples will be collected from those who have provided genetic counseling and undergone genetic tests, etc. at Cancer Institute Hospital (including those who have not yet developed cancer). The participants of observational studies using clinical information are those who have undergone genetic counseling at the Department of Clinical Genetic Oncology, Cancer Institute Hospital, either in person or online, or who have undergone BRCA1/2 testing, homologous recombination deficiency (HRD) testing, microsatellite instability (MSI), or other tests as part of their cancer treatment in our hospital. And also those who have undergone cancer genomic profiling tests such as FoundationOne CDx, OncoGuide diagnostic system, NCC OncoPanel system, FoundationOne Liquid CDx, etc. and other research analyses (including whole genome analysis) in our hospital, by visiting the Cancer Institute Hospital Genome Clinical Department.
Exclusion criteria
Exclusion criteria: The withdrawal request will not be accepted if the research is in progress at the time the withdrawal request is made, the information has already been analyzed and entered into a public database, or the information cannot be connected to a person as a result of processing to prevent identification of a specific person. The possibility that the sample or information cannot be disposed of even if a withdrawal request is made is stated in the explanatory documents. The information should be explained in the explanatory document.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extract electronic and paper medical records from each departmental system. a. Clinical findings (age, sex, height, weight, tumor differentiation, information on medical history, clinical stage, test results, imaging results, etc.) b. Treatment and prognostic information: drugs administered, response, duration of treatment, presence or absence and details of radiotherapy and surgery, presence or absence of recurrence/metastasis, form of recurrence, date of confirmation of recurrence, outcome (alive, death from primary/unknown disease, death from other disease, date of confirmation), etc. c. Genetic test details, analysis data, variant information, and results (including revised reports) d. genealogical information (family history, family tree, information on diseases of family members, etc.) e. Descriptive records on medical records (genetic counseling records, questionnaires, interview records, etc.) | — |
Countries
Japan
Contacts
Public ContactArisa Ueki
The Cancer Institute Hospital of JFCR Department of Clinical Genetic Oncology
Outcome results
None listed