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The effect of low tidal volume to dynamic arterial elastance in the laparoscopic surgery

The effect of low tidal volume to dynamic arterial elastance in the laparoscopic surgery - The effect of low tidal volume to dynamic arterial elastance in the laparoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000054061
Enrollment
60
Registered
2024-04-04
Start date
2024-04-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic surgery patient with inserted arterial line during general anesthesia

Interventions

Bolus infusion of 250ml of Ringers solution

Sponsors

Jichi medical university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Scheduled laparoscopic surgery patients with scheduled arterial catheter insertion and cardiac output monitoring..

Exclusion criteria

Exclusion criteria: Patients with cardiac ejection fraction less than 40% / patients with atrial fibrillation / patients with severe COPD / patients with right heart failure / highly obese patients (BMI>35) / highly classically thin patients (BMI<15) / supine surgery / side lying surgery / surgery requiring isolated lung ventilation / patients not using laparoscopy.

Design outcomes

Primary

MeasureTime frame
In laparoscopic surgery patients undergoing general anesthesia with an inserted arterial line, when patients had mean arterial pressure less than 65mmHg and SVV >10%, the Ea dyn at each point will be measured by varying the volume of ventilation from 8 ml/ideal body weight to 6 ml/ideal body weight. The Ea dyn at each point will be measured. Afterwards, 250 ml of Ringer's solution will be administered rapidly, and patients with a 10% or greater increase in mean arterial pressure will be defined as responders.

Countries

Japan

Contacts

Public ContactYUSUKE IIZUKA

Jichi medical university, saitama medical center Department of anesthesiology and critical care medicine

zukarinn@gmail.com+81486472111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026