Asthma
Conditions
Interventions
Patients will receive dietary intervention based on the specific suggestions of the dietitian for 4 weeks from the start of the intervention
the strict dietary intervention period. Recipes supervised by a dietitian from Oishi-Kenko will be proposed to the patients based on nutritional guidance for obesity, diabetes, dyslipidemia, and hype
taking tree nuts/soy products. Send a daily evaluation of their ability to follow the suggested diet to the dietitian and receive feedback and guidance from the dietitian. The diet during the perio
which is assumed to be approximately 30% of the 4-week period of the strict diet intervention period. After the 4-week period, it is not mandatory to practice the eating behaviors proposed during the
Sponsors
Keio University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who have been diagnosed with bronchial asthma in the past, are able to visit Keio University Hospital, and meet one of the following criteria Obesity with a BMI of 25 or more Type 2 diabetes with HbA1c less than 8%. Dyslipidemia Hyperuricemia The above conditions do not require the applicant to be a patient at Keio University hospital. If the patient has an outpatient clinic, obtain verbal consent from the attending physician.
Exclusion criteria
Exclusion criteria: Pregnant or lactating mothers Chronic kidney disease Grade 3a or higher or renal failure with eGFR less than 59 ml/min/1.73m2 Type 1 diabetes mellitus, type 2 diabetes mellitus on insulin, or type 2 diabetes mellitus with HbA1c of 8% or higher Patients with hypertension that is judged to be poorly controlled by the clinician Other conditions for which the clinician determines that the diet recommended in this study may be associated with exacerbation of the underlying disease Those who cannot give their consent to participate in the study. Those who have difficulty using the contents of the Oishii Kenko App
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in AQLQ (Asthma Quality of Life Questionnaire) from baseline after 4 weeks of dietary intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in weight and body composition assessment using InBody at the start of the dietary intervention (0 weeks), 4 weeks, and 8 weeks The following questionnaire items at the start of dietary intervention (week 0), 2, 4, and 8 weeks Self-assessment of compliance with nutritional guidance Dietary survey including frequency of consumption of fermented foods, etc. Asthma control (ACQ-5) Asthma Quality of Life Questionnaire (AQLQ) Gastroesophageal reflux symptoms (FSSG) Depression and anxiety (HADS) Questionnaire items of the following items at the start of the dietary intervention (week 0) and at week 8 Nutritional Questionnaire prepared by the National Institute of Biomedical Innovation, National Institute of Health and Nutrition (Questionnaire used for analysis of intestinal bacteria) Questionnaire prepared by the National Institute of Biomedical Innovation and Nutrition (Questionnaire used for analysis of intestinal bacteria) The following laboratory indices at the start of the dietary intervention (week 0), at 4 weeks, and at 8 weeks: Blood samples: (peripheral blood, fractionated), TARC, inhaled antigen-specific IgE, total IgE) LDL-C, HDL-C, lipoprotein, triglycerides, HbA1c, insulin, C-peptide, uric acid, zinc Respiratory function tests: spirometry-assessed lung air volume fraction, effort lung capacity Respiratory function tests: respiratory resistance evaluated by spirometry, respiratory reactance Exhaled nitric oxide concentration (FeNO) | — |
Countries
Japan
Contacts
Public ContactKatsunori Masaki
Keio University School of Medicine Division of Pulmonary Medicine, Department of Medicine
Outcome results
None listed