Obstructive sleep apnea syndrome Healthy adults
Conditions
Interventions
Inspiratory muscle exercise Inspiratory muscle loading device Target intensity: 70-75% of maximal inspiratory mouth pressure Frequency and time: 5 sets of 6 breaths with 2 min set rest, a total of
Sponsors
Sapporo Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Men and women aged 40-80 with a diagnosis of obstructive sleep apnea Healthy men and women aged 40-80 years without a diagnosis of obstructive sleep apnea
Exclusion criteria
Exclusion criteria: Currently have or are being treated for any of the following Chronic heart failure, asthma, restricting and obstructive ventilation disorders, central and peripheral nervous system disorders, diabetes mellitus (HbA1c > 7%), hypothyroidism, immunodeficiency disorders Head, neck, or chest surgery within the past 3 years Body Mass Index (BMI) greater than 40 or less than 18.5 Apnea Hypopnea Index (AHI) greater than 15 during treatment within the past year Mixed (obstructive and central) sleep apnea Resting blood pressure greater than 160/100 mmHg or less than 100/60 mmHg Exercise at least 5 times a week at a moderate intensity or higher Current smokers, <Healthy adults> Subjects who have smoked within the past 5 years. <Women> Currently undergoing hormone therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Flow-mediated dilation | — |
Secondary
| Measure | Time frame |
|---|---|
| Maximum inspiratory mouth pressure Maximum expiratory mouth pressure Forced vital capacity Forced expiratory volume in 1 second Cerebrovascular CO2 reactivity | — |
Countries
Japan
Contacts
Public ContactErika Iwamoto
Sapporo Medical University Department of Physical Therapy, School of Health Science
Outcome results
None listed