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Alteration of T-cell immunity by yogurt containing exopolysaccharide (EPS)

Alteration of T-cell immunity by yogurt containing exopolysaccharide (EPS) - Alteration of T-cell immunity by yogurt

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000054016
Enrollment
100
Registered
2024-04-01
Start date
2024-04-15
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer

Interventions

Test Food Meiji Probio Yogurt R-1 Drink Type 112 g (provided free of charge by Meiji Holdings) Consume one bottle of the test food once a day for 28 days. The time of intake is free.

Sponsors

Saitama Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients diagnosed with non-small cell lung cancer (2) Patients who are 20 years of age or older at the time of consent (3) Patients whose written consent for this study has been obtained.

Exclusion criteria

Exclusion criteria: (1) Patients with psychosis/psychiatric symptoms that make it difficult for them to participate in this study (2) Patients with milk allergy (3) Patients with poorly controlled diabetes mellitus (4) Patients who do not wish to consume Meiji Probio Yogurt R-1 (5) Other patients who are deemed inappropriate for the study by the physician in charge.

Design outcomes

Primary

MeasureTime frame
CCR6-positive T cells (CD8+, CD4+) in blood

Secondary

MeasureTime frame
Changes in T-cell cluster proportions, changes in expression of functional molecules in each T-cell cluster, immunohistochemical staining analysis of lung cancer biopsy specimens

Countries

Japan

Contacts

Public ContactHisao Imai

Saitama Medical University International Medical Center Div. of Respiratory Medicine

hisao725@saitama-med.ac.jp042-984-4511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026