Healthy adult male/female
Conditions
Interventions
Consume 16 g/day of research food for 12 weeks
Sponsors
Metagen, Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) At informed consent, male/female subjects aged more than or equal to 20, and less than 65 years old. (2) 25=<BMI<30 kg/m^2 at informed consent. (3) Average number of steps per day is less than 10,000 steps. (4) No metal (pacemaker, etc.) in their body and are able to take CT scan. (5) Subjects who can show their understanding of the study procedure and agreement with participating in the study by written informed consent prior to the study.
Exclusion criteria
Exclusion criteria: (1) Subjects who are unable to discontinue consumption of foods for specified health uses, foods with function claims, health foods (including supplements) that may affect the research (anti-obesity, lipid metabolism, appetite control, intestinal regulation, etc.) from the time consent is obtained. (2) Subjects who have taken drugs (antibiotics, antiflatulent, laxatives, etc.) that would affect the study one month prior to the pre-test. (3) Subjects who plan to take drugs that will affect the research during the study. (4) Subjects with a history of appendectomy. (5) Subjects who have undergone surgery that may affect the study (colonoscopy, removal of gallstones or gall bladder, gastric bypass surgery, bariatric surgery, etc.) within 6 months prior to obtaining consent. (6) Subjects undergoing dietary restriction or weight loss. (7) Subjects who plan to lose weight during the study. (8) Subjects who are expected to undergo a major change in their family, work, or other living environment (e.g., relocation, transfer, etc.) during the study. (9) Subjects with extremely irregular eating habits. (10) Subjects with special dietary habits (vegetarian, vegan, low-carbo). (11) Subjects whose roommates plan to participate in the study. (12) Smokers. (13) Heavy alcohol drinkers. (14) Subjects with previously diagnosed diabetes mellitus (type 1/type 2) or dyslipidemia. (15) Subjects with a history of serious diseases of the heart, liver, kidneys, digestive organs, etc. (16) Pregnant, lactating, or intending to become pregnant during the study. (17) Subjects allergic to medicines and foods. (18) Subjects who are aware of excessive abdominal symptoms (severe diarrhea or bloating) when ingesting oligosaccharides. (Due to character limitation, the following will be listed in the "Others" section)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abdominal fat area | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Gut microbiota 2. Gut metabolomes 3. Defecation status (frequency, quantity, property, color, feeling of incomplete evacuation, abdominal pain, odor of defecation) 4. Abdominal symptoms (bloating, belching, gas) at times other than during defecation 5. Body weight, BMI, waist circumference, body composition 6. OSA-MA 7. POMS2 short version 8. GLP-1, PYY | — |
Countries
Japan
Contacts
Public ContactFumiko Nakamura
CPCC Company Limited Clinical Support Division
Outcome results
None listed