Ovary cancer
Conditions
Interventions
Low-pressure ventilation and low venous pressure interventions are continued from the start of surgery until the end of surgery. The intervention group is managed with zero PEEP and TV 6 ml/kg, and p
Sponsors
Chiba University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients undergoing ovarian cancer surgery at Chiba University Hospital.
Exclusion criteria
Exclusion criteria: 1.Minors 2.Emergency surgery 3.Patients for whom an experimental laparotomy will be performed in this surgery 4.Obese with a BMI of 30 or more 5.Patients diagnosed with chronic obstructive pulmonary disease 6. Patients under treatment for asthma (included in eligible patients if only pre-existing) 7.Patients with complications of heart failure 8.Patients with severe sleep apnoea syndrome 9.Smokers (if they have not stopped smoking for at least one month) 10.Anaemia Hb <9g/dl 11.Coagulation abnormalities APTT > 42 seconds, PT > 17 seconds 12.Platelets <100,000 13.Patients with preoperative physical status 4 or 5 of the American Society of Anaesthesiologists 14.Patients with a history of laparotomy (excluding exploratory laparotomy due to ovarian cancer) 15.Patients with ChildB or C cirrhosis 16.Patients deemed unsuitable as subjects by the principal (sub)investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraoperative blood loss | — |
Secondary
| Measure | Time frame |
|---|---|
| Estimated blood loss Perioperative transfusion volume and transfusion rate Estimated and actual ascites volume Postoperative chest x-ray for atelectasis Estimated blood loss at 1 week post-operatively Respiratory events at 1 week postoperatively Postoperative complications Clavien-Dindo classification at 1 week and 30 days Length of hospital stay In-hospital mortality | — |
Countries
Japan
Contacts
Public ContactKyongsuk Son
Chiba-University Hospital Department of Anesthesiology
Outcome results
None listed