Multiple prengancy
Conditions
Interventions
Reduction surgery is performed by puncturing the uterus with a needle guided by transabdominal ultrasound between the 11th and 13th weeks of pregnancy and injecting potassium chloride into the fetal h
Sponsors
The University of Osaka
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Pregnant women who have visited our department before 14 weeks of gestation. 2. Individuals who, along with their partners, are capable of providing written consent for participation in the clinical study. 3. Participants aged 18 or older but younger than 50, with partners aged 18 or older. 4. Individuals with complications expected to significantly harm maternal health if the pregnancy continues, such as high-order multiple pregnancies or twin pregnancies. 5. Individuals without genital bleeding. 6. Individuals without ruptured membranes. 7. Individuals with a cervical length of 20 mm or more.
Exclusion criteria
Exclusion criteria: 1. Individuals who test positive for HIV antibodies, HCV antibodies, or HBs antigen. 2. Individuals with psychiatric illness or symptoms that make participation in and continuation of the trial difficult. 3. Individuals with poor overall health status, classified under the American Society of Anesthesiologists Preoperative Physical Status Classification as ASA-PS Class 3, 4, 5, or 6.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Successful rate of selective reduction surgery on the day after the operation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number of surviving fetuses one week after the surgery. 2. Psychological evaluation of subjects one week after the surgery. 3. Number of adverse events occurring within one week post-surgery. | — |
Countries
Japan
Contacts
Public ContactKazuya Mimura
Osaka University Hospital Department of Obstetrics and Gynecology
Outcome results
None listed