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Time-dependent neural arbitration of stress memories

Time-dependent neural arbitration of stress memories - Time-dependent neural arbitration of stress memories

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000053938
Enrollment
20
Registered
2024-03-25
Start date
2024-03-23
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-traumatic stress disorder

Interventions

Participants are asked to pay attention to audio, still images, and videos, lasting approximately 1 to 5 minutes, played on a monitor or through VR playback devices. During this, we measure intracrani

Sponsors

Osaka University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ndividuals who have electrodes placed around the hippocampus or amygdala for clinical reasons. Those who are between the ages of 18 and under 50 at the time of consent. Participants who have provided written consent to participate in the study. Patients who are capable of giving consent themselves after receiving explanations through oral, written, or video formats.

Exclusion criteria

Exclusion criteria: Patients with significant cognitive impairments. Patients currently undergoing treatment for any psychiatric disorder, those undergoing treatment for or with a history of PTSD, and individuals with a strong aversion to severe accidents such as traffic accidents. Others deemed unsuitable by the principal investigator or co-investigators of the study.

Design outcomes

Primary

MeasureTime frame
We analyze the relationship between the duration, frequency, and amplitude of waveforms such as sharp wave ripples (SWRs), and the results of thought content surveys, as well as physiological responses like skin conductance, pulse rate, and respiration, using regression analysis and other statistical methods.

Countries

Japan

Contacts

Public ContactTakufumi Yanagisawa

Osaka University Neurosurgery

tyanagisawa@nsurg.med.osaka-u.ac.jp06-6879-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026