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Exploring factors contributing to the efficacy of adhesion molecule inhibitors for ulcerative colitis: a multi-center study in Japan

Exploring of factors contributing to the efficacy of adhesion molecule inhibitors for ulcerative colitis: a multi-center study in Japan - FAMILIA Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000053935
Enrollment
10
Registered
2024-05-01
Start date
2024-05-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis

Interventions

None listed

Sponsors

Kyorin University School of Medicine
Lead Sponsor
Sapporo Medical University, Dept. Gastroenterology and Hepatology Toho University Sakura Medical Center, Dept. Gastroenterology and Hepatology Kitasato University Kitasato Institute Hospital, Dept. Gastroenterology and Hepatology
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1)Subjects diagnosed with ulcerative colitis. (2)Subjects who are naive to molecular-targeted medications and plan to start adhesion molecule inhibitors. (3)Subjects who are 16 years old or older when providing written consent. (4)Subjects who understand, decide to take part in this study and provide written consent by themselves. Minors need consent from themselves as well as their guardians.

Exclusion criteria

Exclusion criteria: (1)Subjects who don't provide written consent by themselves or their guardians. (2)Subjects who had total or partial colectomy. (3)Subjects diagnosed with proctitis or an undetermined disease type. (4)Subjects suspected concomitant colitis due to other reasons. (5)Subjects with an emergent, critical condition of ulcerative colitis (e.g., fulminant UC, toxic megacolon, uncontrollable bleeding).

Design outcomes

Primary

MeasureTime frame
exploring the factors related to the endoscopic improvement at 6 months after starting the remission induction therapy.

Countries

Japan

Contacts

Public ContactJun Miyoshi

Kyorin University School of Medicine Department of Gastroenterology and Hepatology

jmiyoshi@ks.kyorin-u.ac.jp0422-47-5511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026