Examination of changes in swallowing and articulation-related brain activity in patients after head and neck cancer surgery

Examination of changes in swallowing and articulation-related brain activity in patients after head and neck cancer surgery - Examination of changes in swallowing and articulation-related brain activity in patients after head and neck cancer surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000053913

Enrollment

Registered

2024-03-20

Start date

2024-07-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

head and neck cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. No history of neurological disorders. 2. Ability to understand the explanation and provide confirmed consent. 3. Physique that allows for the wearing of headgear.

Exclusion criteria

Exclusion criteria: 1. Presence of cognitive impairments that make it difficult to understand explanations or instructions. 2. History of neurological disorders. 3. Individuals currently undergoing treatment for recurrence or metastasis in the head and neck area. 4. Post-operative head and neck cancer patients who have not undergone laryngectomy or free flap reconstruction surgery.

Design outcomes

Primary

Measure	Time frame
Electroencephalography (EEG) measurements will be taken six months after surgery for head and neck cancer. The EEG will be used to calculate the amplitude (power) during swallowing and articulatory movements. The power of the EEG is considered to be related to the activity level of brain neurons.	—

Secondary

Measure	Time frame
1. Evaluation of Aspiration and Pharyngeal Residue with Food: The Aspiration-Residue (AsR) score, as referenced in the literature, will be utilized to evaluate aspiration and pharyngeal residue during videofluoroscopic swallowing studies (VFSS) with food. This is a simplified evaluation method for VFSS after treatment for head and neck cancer. It quantifies the degree of aspiration ("As" for aspiration) and pharyngeal residue ("R" for residual) on a scale of up to 10 points, with lower scores indicating more severe dysphagia. 2. Speech Clarity: Articulatory function will be evaluated on a 5-point scale, where 1 represents clear speech, 2 indicates occasional unintelligible words, 3 suggests the listener can understand if they are familiar with the topic, 4 means only occasional words are understandable, and 5 indicates completely incomprehensible speech.	—

Measure

Time frame

1. Evaluation of Aspiration and Pharyngeal Residue with Food: The Aspiration-Residue (AsR) score, as referenced in the literature, will be utilized to evaluate aspiration and pharyngeal residue during videofluoroscopic swallowing studies (VFSS) with food. This is a simplified evaluation method for VFSS after treatment for head and neck cancer. It quantifies the degree of aspiration ("As" for aspiration) and pharyngeal residue ("R" for residual) on a scale of up to 10 points, with lower scores indicating more severe dysphagia. 2. Speech Clarity: Articulatory function will be evaluated on a 5-point scale, where 1 represents clear speech, 2 indicates occasional unintelligible words, 3 suggests the listener can understand if they are familiar with the topic, 4 means only occasional words are understandable, and 5 indicates completely incomprehensible speech.

—

Countries

Japan

Contacts

Public ContactAtsushi Suehiro

Graduate School of Medicine, Kyoto University Department of Otolaryngology, Head & Neck Surgery

a_suehiro@ent.kuhp.kyoto-u.ac.jp075-751-3346

Outcome results