Superior vena cava syndrome
Conditions
Interventions
None listed
Sponsors
National Hospital Organization Nagoya Medical Center Department of respiratory medicine
National Hospital Organization Okayama Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Superior vena cava syndrome is classified as Grade 0 to 5. Grade 0 is asymptomatic (radiographic evidence of superior vena cava obstruction in the absence of signs and symptoms); Grade 1 is mild (edema of head or neck, cyanosis, plethora ); Grade 2 is moderate edema of head or neck with functional impairment accompanied by symptoms such as mild dysphagia, cough, temporomandibular joint disorder, or visual disturbances due to eyelid edema; Grade 3 is severe (mild or moderate cerebral edema (headache, dizziness) or mild to moderate laryngeal edema or diminished cardiac reserve (syncope after bending)); Grade 4 is life-threatening; substantial cerebral edema (confusion, obtundation) or substantial laryngeal edema (stridor) or substantial hemodynamic compromise (syncope without precipitating factors, hypotension, insufficiency); Grade 5 is fatal. In this study, patients with any grades are eligible. 2. The patients who previously received preoperative steroids underwent rigid bronchoscopic intervention. The patients who were already taking steroids were eligible, but they need to receive additional preoperative steroids. 3. The patients who will undergo tumor resection using a rigid bronchoscope under general anesthesia have planned assistance with electric snare, APC, cryoprobe or ballooning, airway stent placement, or removal of a foreign body. 4. Patients older than 20 years 5. Informed consent
Exclusion criteria
Exclusion criteria: 1. The patients who have difficulty responding to the VAS before and after rigid bronchoscopic intervention 2. The patients who are not eligible as agreed by investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence rate of glottic edema and extubation failure that occurred within 24 hours of rigid bronchoscopic intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To evaluate the patient's symptoms (VAS scale) 2. To evaluate the relationship between the stridor and extubation failure 3. To evaluate the relationship between glottic edema, the external diameter of the rigid bronchoscope, and operation time 4. To evaluate the relationship between postoperative glottic edema and the type and external diameter of airway stents 5. To evaluate the relationship between the grade of superior vena cava syndrome, glottic edema, and extubation failure 6. To evaluate the relationship between type, dosage, and administration time of preoperative steroids and postoperative glottic edema | — |
Countries
Japan
Contacts
Public ContactATSUSHI TORII
National Hospital Organization Nagoya Medical Center Department of respiratory medicine
Outcome results
None listed