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Non-randomized controlled trial on the frequency of hen's egg protein ingestion during early infancy and its effect on preventing the development of hen's egg allergy

The frequency of hen's egg ingestion during early infancy for prevention of hen's egg allergy - FREIN

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000053850
Enrollment
202
Registered
2024-03-13
Start date
2024-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

food allergy, hen&#39

Interventions

Participants of daily ingestion group intake 12.5 mg of hen&#39
s egg protein everyday during first 4 weeks at 4 months of age, and 25 mg of hen&#39
s egg protein everyday during next 4 weeks. They will be treated their eczema with proactive treatment using topical corticosteroids. They will be performed oral food challenge test at 6 months of age
s egg allergy. Participants of weekly ingestion group intake 12.5 mg of hen&#39
s egg protein once a week during first 4 weeks at 4 months of age, and 25 mg of hen&#39
s egg protein once a week during next 4 weeks. They will be treated their eczema with proactive treatment using topical corticosteroids. They will be performed oral food challenge test at 6 months of
s egg allergy. Participants of avoidance group eliminate hen&#39
s egg protein up to 6 months of age. They will be treated their eczema with proactive treatment using topical corticosteroids. They will be performed oral food challenge test at 6 months of age to ass
s egg allergy.

Sponsors

Social medical corporation KARIYUSHIKAI Heartlife Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Gestationa age>=35 weeks and birth weight>=2000g Presence of visible eczema

Exclusion criteria

Exclusion criteria: Complication of any severe underlying disease

Design outcomes

Primary

MeasureTime frame
The proportion of hen's egg allergy development at 6 months of age

Secondary

MeasureTime frame
The proportion of hen's egg sesitization and measurement of hen's egg specific IgE and IgG4 titer at 6 months of age

Countries

Japan

Contacts

Public ContactTetsuhiro Sakihara

Social medical corporation KARIYUSHIKAI Heartlife Hospital Pediatrics

odekorin2000@yahoo.co.jp0988953255

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026