Psychosocial Effects of Cachexia for Older Adults with Advanced Lung and Gastrointestinal Cancer: An Observational Study

Psychosocial Effects of Cachexia for Older Adults with Advanced Lung and Gastrointestinal Cancer: An Observational Study - Psychosocial Effects of Cachexia for Older Adults with Advanced Lung and Gastrointestinal Cancer: An Observational Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000053843

Enrollment

Registered

2024-03-14

Start date

2021-08-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer cachexia or cancer-associated cachexia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) participant was at least 70 years on the date of consent 2) participant was ECOG-PS (Eastern Cooperative Oncology Group Performance Status) of 0-2 3) participant was non-small cell lung cancer or small cell lung cancer at clinical stage III/IV or recurrent after radical surgery/radiotherapy 4) participant was scheduled for initial chemotherapy 5) participant has CT images imaging the third lumbar level 6) participants have given written consent 7) participant was able to read and write Japanese 8) participant was expected to survive at least 12 weeks after the start of treatment.

Exclusion criteria

Exclusion criteria: 1) Participant's weight change in the 6 months prior to enrollment was unknown 2) Participant was scheduled to undergo surgical treatment within 3 months from the time of enrollment 3) Participants with psychiatric or neurological symptoms that make it difficult to complete the questionnaire accurately.

Design outcomes

Primary

Measure	Time frame
Association between cancer cachexia and eating-related distress (Baseline, 4-8 weeks, 10-14 weeks)	—

Secondary

Measure	Time frame
1) Association between cancer cachexia and EORTC QLQ-CAX24 (Baseline, 4-8 weeks, 10-14 weeks) 2) Association between cancer cachexia and EORTC QLQ-C30 (Baseline, 4-8 weeks, 10-14 weeks) 3) Association between geriatric assessment and eating-related distress (Baseline, 4-8 weeks, 10-14 weeks) 4) Association between severity of cancer cachexia and eating-related distress (Baseline, 4-8 weeks, 10-14 weeks) 5) Interrelationship between patient characteristics, geriatric assessment, severity of cancer cachexia, mGPS, LSMI, EORTC QLQ-CAX24, EORTC QLQ-C30, eating-related distress(Baseline, 4-8 weeks, 10-14 weeks) 6) Association between severity of cancer cachexia, mGPS, LSMI, EORTC QLQ-CAX24, EORTC QLQ-C30, eating-related distress(Baseline, 4-8 weeks, 10-14 weeks) 7) Interview about distress related to eating and weight loss should be described in a way that does not compromise the patient's intentions. (Baseline, 10-14 weeks)	—

Measure

Time frame

1) Association between cancer cachexia and EORTC QLQ-CAX24 (Baseline, 4-8 weeks, 10-14 weeks) 2) Association between cancer cachexia and EORTC QLQ-C30 (Baseline, 4-8 weeks, 10-14 weeks) 3) Association between geriatric assessment and eating-related distress (Baseline, 4-8 weeks, 10-14 weeks) 4) Association between severity of cancer cachexia and eating-related distress (Baseline, 4-8 weeks, 10-14 weeks) 5) Interrelationship between patient characteristics, geriatric assessment, severity of cancer cachexia, mGPS, LSMI, EORTC QLQ-CAX24, EORTC QLQ-C30, eating-related distress(Baseline, 4-8 weeks, 10-14 weeks) 6) Association between severity of cancer cachexia, mGPS, LSMI, EORTC QLQ-CAX24, EORTC QLQ-C30, eating-related distress(Baseline, 4-8 weeks, 10-14 weeks) 7) Interview about distress related to eating and weight loss should be described in a way that does not compromise the patient's intentions. (Baseline, 10-14 weeks)

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Countries

Japan

Contacts

Public ContactTateaki Naito

Shizuoka Cancer Center Division of Thoracic Oncology

t3naito@gmail.com0559895222

Outcome results