Skip to content

Research aimed at the development of early cancer detection methods by comprehensively examining changes in DNA, RNA, proteins, metabolites, and the microbiome.

Clinical Development of Molecular Residual Disease (MRD) and Multi-Cancer Early Detection (MCED) using Liquid Biopsy Multiomics Based on Artificial Intelligence (AI) - Clinical Development of Molecular Residual Disease (MRD) and Multi-Cancer Early Detection (MCED) using Liquid Biopsy Multiomics Based on Artificial Intelligence (AI)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000053815
Enrollment
1400
Registered
2024-03-09
Start date
2024-03-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer

Interventions

None listed

Sponsors

National Cancer Center Hospital East
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) The participant must have participated in the CONDUCTOR study as of March 2025, have not withdrawn consent, and have not refused secondary use of the information or sample. 2) Participants in the CONDUCTOR study must be at least 18 years old. 3) You have participated in the "Tohoku Medical Megabank Project Three Generations Cohort Study" or "Tohoku Medical Megabank Project Community Cohort Study" (hereinafter referred to as "ToMMo") between May 2013 and March 2025, have not withdrawn your consent, and have not refused secondary use of information and samples. In addition, if blood samples are to be collected for a clinical performance study, written consent for participation in this study has been obtained from the individual based on his/her voluntary will. 4) There is no history of malignancy in the ToMMo main body study participants in 3). 5) The ToMMo main study participant in 3) must be between 20 and 75 years of age.

Exclusion criteria

Exclusion criteria: The person in charge of this research is judged as not having sufficient ability to make decisions regarding the implementation of this research.

Design outcomes

Primary

MeasureTime frame
To evaluate the clinical performance (sensitivity, specificity, etc.) of the developed MRD and MCED assays

Secondary

MeasureTime frame
To evaluate the clinical performance (sensitivity, specificity, etc.) of the developed MRD and MCED assays by cancer type, clinical stage, etc.

Countries

Japan

Contacts

Public ContactTaro Shibuki

National Cancer Center Hospital East Department for the Promotion of Drug and Diagnostic Development

tshibuki@east.ncc.go.jp04-7133-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026