Trauma patients with hemorrhagic shock (suspected)
Conditions
Interventions
Early administration of vasopressor
Conventional treatment
Sponsors
Tokyo Medical and Dental University Trauma and Acute Critical Care Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients with trauma who suffered hemorrhagic shock (suspected)
Exclusion criteria
Exclusion criteria: 1. Patients with prehospital cardiac arrest 2. Patients who have been on vasopressors at other hospital 3. Patients who refuse to participate in the trial 4. Patients deemed ineligible to participate by a clinical physician 5 .Patients who have the advanced directives restricting implementation of the standard critical care
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exsanguination at 24 hours after intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Total amount of transfusion and infusion volume 2. Incidence rates of adverse events (arrhythmia, thrombosis, ischemia, or hemorrhage) during the 72 hours after intervention 3. All-cause mortality rate at 28 days 4. Ventilator-free days at 28 days after intervention 5. All-cause mortality at 90 days after intervention | — |
Countries
Japan
Contacts
Public ContactWataru Takayama
Tokyo Medical and Dental University Tokyo Medical and Dental University Department of Acute Critical Care and Disaster Medicine, Graduat
Outcome results
None listed